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Frozen vs. Ambient
Which reagent delivery method do you prefer? We offer a wide range of reagent lyophilization services options.
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Lyophilization is also knows as freeze drying. It is a dehydration process that takes place after a product has been frozen. Lyophilization is gaining popularity in the life sciences for reagents and assays due to its numerous benefits, including cost-reduction, shelf-life extension and ease-of-use.
Less warehouse space required, lower electrical and equipment costs, reduced environmental impact. Ambient shipping is easier, more flexible in todays more complex shipping environment.
Shipments, even with critical enzymes, can be bumped off flights due to weight and dry ice. Lyophilization eliminates worry of temperature variations with your shipped product. No more dry ice delays. Prevent excess or obsolete Inventory.
Lyophilized reagents, enzymes, beads and antibodies have been shown to be stable for years in lyophilized format. Stab-tests show antibodies >20 years old that perform like the day they were lyophilized.
Eliminate difficult small-volume pipetting steps. Fewer user errors through reduced mixing steps & service calls.
Eliminate styrofoam coolers and dry ice. Your product ships in recyclable containers, and will boost your environmental goals and regulatory compliance. Ambient shipping means reduced costs and lower carbon footprint with less packaging, fuel, and transportation needed.
Argonaut is the exclusive producer of LyoDose beads, a proprietary spherical lyophilized bead format that contains a specified volume of reagent.
was established because lyophilization development and production requires specialized expertise. Argonaut’s team can take you from liquid reagents to a fully lyophilized assay within weeks, reducing your time to market. Benefits, including extended shelf-life and ease-of-use.
From small to large scale projects. From Life sciences and applied markets to high-scale commercial products, and highly regulated clinical IVD products.
Setting up an in-house lyophilization facility requires significant investment of time and resources. Accelerate your project at a lower cost. Working with our full-service infrastructur, your project has access to:
Proprietary lyophilization technology
A: Lyophilization is also known as freeze drying. It is a dehydration process that takes place after a product has been frozen. Lyophilization is gaining popularity in the life sciences for reagents and assays due to its numerous benefits, including extended shelf-life and ease-of-use.
A. Argonaut offers a wide range of reagent lyophilization services options. Our most popular format is LyoDose™ beads, although in situ, vials, and swabs are also common. Drug products are not able to be lyophilized at this time.
A: Argonaut is the exclusive supplier of LyoDose™ beads, which are unit-dose lyophilized spheres. LyoDose™ beads offer significant advantages including faster reconstitution time, improved user experience, and reduced contamination risk.
A: Unfortunately we do not offer pharmaceutical lyophilization services at this time. Please refer to our drug products manufacturing page for our full biopharma capabilities.
A: With a few exceptions, most liquid reagents can be lyophilized. Examples of projects include qPCR reagents, NGS kit components, and molecular diagnostics cartridges.
A: Lyophilization requires careful optimization of parameters. Our lyophilization feasibility program determines the best manufacturing process for your product, prior to full-scale production. The feasibility study produces small batches of lyophilized product with three different excipients (inert components that stabilize products during the lyophilization process), which are then tested. This facilitates selection of the best excipient for optimal lyophilization.
A: Yes, your product can be produced to cGMP compliance. Argonaut offers full cGMP manufacturing capabilities, and our lyophilization equipment is housed within our ISO manufacturing suites.
A: Lyophilization offers many advantages, including cost savings, improved user experience, and environmental responsibility.
A. At production scale, units can be produced inexpensively in the same lyophilizer run. The initial investment in lyophilization services is quickly repaid with reduced cold chain expenses, fewer user errors, and longer expiration windows.
A. Turnaround times on lyophilization are usually quick, often 1-2 weeks. If you plan to manufacture under cGMP please allow time for documentation and technology transfer.
Formulations containing high levels of glycerol or salt are difficult to lyophilize. Click the link below to contact us and we can provide suggestions tailored to your specific reagents.
A. Lyophilization is a complex process that requires extensive optimization. Argonaut has decades of experience in setting these parameters and selecting excipients. As a result, our lyophilization feasibility program has a high success rate in achieving a suitable product.
Which reagent delivery method do you prefer? We offer a wide range of reagent lyophilization services options.